According to the International Diabetes Federation, 536.6 million adults (20 to 79 years old) were estimated to have diabetes in 2021. Among several comorbidities, depression and bone health in diabetes patients are generally disregarded in the management of diabetes. About 10.2% of women in the global population have diabetes, and 27% of them have depressive disorders.
The psychological burden of diabetes, hypothalamic-pituitary-adrenal axis activation, sleep disturbance, inflammation, and poor lifestyle are associated with depression in diabetes patients. In addition, skeletal fragility is also associated with diabetes due to obesity, impaired glucose metabolism, the toxicity of glucose oxidative derivatives, impaired muscle endocrine function and bone microvascular function, sarcopenia, and diabetes medications. To learn more about depression and bone health in diabetes, join the…
