While rummaging through a wide array of literature on Google and trying to fit in bits and pieces of information which have come partially from the expertise and partially from experience as a clinical pathologist I came across this publication from IMMUNOLOGY( click here ) a journal published by the British Society of Immunology way back in 1991. This proposed model answers the various aspects of HIV infection and in a way challenges the contemporary theories is a must read for all interested clinicians, pathologists, transfusion medicine specialists, and microbiologist.
Some of the salient points raised include: There is a high degree of molecular mimicry between MHC molecules(especially MHC class II)on the cell surface and the various glycoprotein molecules implicated in HIV such as gp 120 and gp41. This supports the idea that HIV can be regarded as an autoimmune disease induced by…
