As previously we used to say a patient with repeated sickness, is immunity is low but now scientifically Indoor allergens as dust, dust mites, molds in air conditioners, malls will have decreased immunity as well food intolerance will cause repeated GI symptoms. Metals have a multi-focal dynamic relationship with "autoimmunity" Metals such as nickel can cross the cell and nuclear membranes and ionically bind DNA into atypical formations which may produce atypical RNA. Lupus-prone animals can have exacerbations when exposed to metals such as Hg, Cr, Co, and sometime Ni. My introduction was with a patient with SLE who became treatment-resistant.
She had developed SLE after a dental tool was broken and lodged in her tooth. She was epicutaneous patch test positive to metals and metal chelators such as salicylates and terpenes. A lymphocyte activation assay showed a logarithmic…
