Diabetes mellitus (DM) is a chronic metabolic disorder that affects patients of various age. Over the years DM has turned out to be a global epidemic and one of the leading cause of deaths worldwide. The number of patients affected by this disease is expected to rise from 415 million to 642 million people worldwide by 2040. DM is a systemic disease that affects an increasingly larger population worldwide.

Patients suffering from diabetes mellitus often suffer from chronic complications of micro and macropathy character which includes the induction of severe organic dysfunctions and may lead to the sudden death of the patient. The hyperglycemic environment during diabetes mellitus leading to adverse health implications includes damage of vascular endothelium, development of chronic inflammation, organic and functional lesions in several systems and organs. For patients with long-lasting…