According to researchers, an asthma drug has the potential to delay development of a rare heart complication. Aortic aneurysm is a serious condition that affects the wall of the aorta resulting in weakness and swelling. The condition is symptom-free Not discovered until late in its development when it ruptures Causes life-threatening hemorrhaging An asthma drug Montelukast, blocks the leukotrienes that drives inflammation causing asthma.
It was observed that patient operated for aortic aneurysm showed high levels of particular leukotrienes in the vascular walls. The effect of these leukotrienes was observed in aortic aneurysm. The study on mice revealed: The treatment with Montelukast on mice reduced the swelling of the aorta Cut levels of an enzyme involved in breaking down the vascular wall Reduced a protein involved in inflammatory processes This drug was safe with few side effects…
