There is only one existing vaccine for TB and it is not effective in adults. Researchers at the Centenary Institute and University of Sydney will next test their new vaccine in clinical trials with humans.They have created and tested a new vaccine type that provides substantial protection against tuberculosis (TB), following more than five years of work and research. The test was a preclinical run using mouse models and raises hope against a disease that kills around 1.6 million people each year.
It is an advanced synthetic vaccine, which takes two small proteins typically found in tuberculosis bacteria, binds them tightly to a stimulant and, not unlike jumpstarting a car, kicks the immune response in the lungs back into working order. “We were then able to show that when this vaccine was inhaled into the lungs, it stimulated the type of T cells known to protect against TB.…
