A 2-year-old baby is awaiting surgery for the repair of pyloric stenosis. His coagulation screen is as follows: PT – 10.8s (9.3 – 11.7s) aPTT – 51s (27.2 – 39.1s) Fibrinogen – 3.0 g/L (1.5 – 4.2 g/L) Thrombin Time – 15s (12 - 16s) The attending surgeon requests a hematology consultation before surgery regarding the prolonged aPTT. aPTTwas repeated to confirm the result, and if still prolonged mixing test was done.
The Corrected aPTT: 37.5s (Normal plasma is added to the test (patient’s) plasma in a 50:50 mix, and the aPTT is repeated) What can you infer from the results of the mixing test? *This Case Challenge is from the Editorial Team of Docplexus and is meant for educational purposes only.
