In this EASD 2025 Annual Meeting podcast episode, Prof. Frédéric Gachon and Prof. Olga Pivovarova-Ramich explore how circadian rhythms orchestrate glucose metabolism, insulin sensitivity, and body weight regulation. The discussion highlights the roles of central and peripheral clocks, emphasizing how late-night eating, shift work, and chronotype misalignment contribute to metabolic dysfunction and elevated diabetes risk.

The speakers contrast meal timing with calorie restriction, reviewing current evidence on intermittent fasting and time-restricted eating. They also address exercise timing as a modifiable factor influencing metabolic outcomes. Together, these insights underscore chrononutrition as an emerging clinical dimension in personalized diabetes prevention and management. Listen to the full episode here to explore how circadian biology, meal timing, and exercise interact to…