Diabetes and cancer are two chronic diseases that significantly impact quality of life and life expectancy worldwide. 1 Emerging evidence suggests that diabetes-related metabolic disorders might play a role in cancer development. 1 While strong evidence for the direct link between diabetes and human cancers is still lacking, recent research indicates that hyperglycemia and hyperinsulinemia can lead to cell damage through mechanisms like glucotoxicity, lipotoxicity, and oxidative stress, 1 which can transform cells and elevate cancer risk.
1 Intriguingly, clinical trials also suggest that anti-diabetes drugs might influence cancer risk through mechanisms that are not yet fully understood. 1 Evidence indicates that cancer patients with diabetes face higher cancer-related mortality rates, and complications arising from diabetes can impact the selection of cancer therapies, underscoring…
