Biomarkers have transformed modern clinical practice by offering objective, quantifiable insights into disease processes. From troponins in cardiac events to inflammatory markers like CRP and procalcitonin, they enable earlier diagnosis, risk stratification, and monitoring of treatment response. With the rise of precision medicine, their role has only expanded, giving clinicians powerful tools to support decision-making. However, their growing prominence has also led to a tendency to over-rely on numbers, sometimes at the cost of the broader clinical picture.
Clinical judgment, on the other hand, remains rooted in experience, pattern recognition, and patient context. It integrates history, examination findings, and subtle cues that may not be captured through investigations. In many real-world scenarios, symptoms and signs do not neatly align with biomarker levels—for instance, patients…
