Brief review on the ocular and systemic associations of keratoconus and it’s ocular causes are Keratoconjunctivitis sicca Retinitis pigmentosa Vernal keratoconjunctivitis Severe rubbing of eyes Leber's amaurosis Congenital cataracts Aniridia Retinopathy of prematurity systemic causes are Blue sclera Osteogenesis imperfecta Downs Turners Ehlers-Danlos syndromes Mental retardation Achondroplasia Marfan's Mitral valve prolapse syndrome Atopic dermatitis