Rising incidences of obesity, arising from carbohydrate-rich diets and sedentary lifestyles, are driving a global pandemic of type 2 diabetes mellitus (T2DM). Therefore, scientists are constantly on the lookout for novel T2DM treatment strategies . A recent study looked at the association between 36 butyrate-producing bacteria and insulin sensitivity, insulin secretion and clearance, disposition index, and rate of dysglycemia in individuals with diabetes and prediabetes (n = 163) and normal glucose tolerance (n = 189).
Species-level analyses showed that ten bacteria had beneficial effects on insulin homeostasis and dysglycemia (Table 1); however, Anaerostipes caccae and Flavonifractor plautii showed adverse effects . ##Table 1. Bacteria with beneficial effects on insulin homeostasis## ## The genus Coprococcus was related to higher insulin sensitivity and disposition index and a lower…
