A retrospective observational cohort study published in Medicina evaluated clinical, electrocardiographic, and cardiac magnetic resonance (CMR) predictors of recurrent myocarditis in 162 young adults with CMR-confirmed acute myocarditis. During 2 years of follow-up, the recurrence rate was 12.3%, with a median time to recurrence of 13.5 months. ST-segment depression on admission electrocardiography (OR: 14.469; 95% CI: 2.416–86.673; p=0.003) and late gadolinium enhancement (LGE) on CMR (OR: 10.362; 95% CI: 1.614–66.549; p=0.014) were independent predictors of recurrence.
Colchicine therapy for at least 3 months was independently associated with a lower recurrence risk (OR: 0.295; 95% CI: 0.098–0.891; p=0.030). Time-to-event analyses confirmed these findings, while multisegmental LGE and winter onset of the index episode were also associated with recurrence. ECG and CMR phenotyping may…