Chronic pancreatitis is a long standing inflamation of the pancreas that alters organ structure and functions with irreversible changes, India has the highest incidence of cp in per lac population (about 200). Pancreas has both exo and endocrine functions, by weight 80% is exocrine and remaining 20% is endocrine, average normal weight of pancreas is 80 grams.
endocrine fuctions served by these cells are like: Alfa cell, produced glucagon Beta cells, insulin Delta cells, somatostatin PP cells, pancreatic polypeptides Exocrine functions are following Bicarbonate ions..to neutrilize gastric acid or chyme(acidic bcz hcl) Enzymes Trypsinogen Chymotrypsinogen Pancreatic amylase and lipase Due to structural and functional damage to pancreas all endo and exo functions are altered,for CP following causes are important: Alcohol: longstanding and overuse Smoking consided as a important cause…
