Synopsis Globally, around 25% to 30% of children with epilepsy suffer from uncontrolled seizures despite antiepileptic drug (AED) treatment. Pediatric patients with focal seizures require careful management because of the fatalities associated with uncontrolled seizures. Lacosamide is an AED with anticonvulsant activity and selectively enhances slow inactivation of voltage-gated sodium channels. The study described below aimed at evaluating the efficacy and tolerability parameters of lacosamide in pediatric focal seizures.
This “MEDFACT” discusses a research study from, “Neurology” titled “Efficacy and tolerability of adjunctive lacosamide in pediatric patients with focal seizures,” Aug 2019 . Authors : Viktor Farkas, Barbara Steinborn, Robert Flamini, Ying Zhang, Nancy Yuen, Simon Borghs, et al. What was the need for this study? The management of pediatric focal seizures can be…
