The section on mental health adverse effects was made more prominent by separating it from the warnings on central nervous system adverse effects and the language was made consistent across the therapeutic class. The specific mental health adverse effects added to or updated include: Disturbances in attention Disorientation Agitation Nervousness Memory impairment Delirium Musculoskeletal adverse reactions included: Arthralgia Abnormal gait Abnormal joint exam Joint sprains Pain in leg, arm, or back Bone pain Myalgia, or decreased range of motion in an ankle, knee, hip, wrist, elbow, or shoulder The use of ciprofloxacin in infants and children requires careful consideration.
While still a very useful option for patients with multi-drug resistant infections susceptible to a fluoroquinolone, it should no longer be considered first-line therapy for uncomplicated infections. Growing concerns…
