Studies in Asian countries have established the significance of Clostridium difficile as a nosocomial pathogen. But sadly, the general lack of awareness and absence of surveillance has let the epidemic go unchecked. The increased rates of hospitalisation, broad spectrum antibiotic usage and emergence of hypervirulent strains have been related to the increased incidence of Clostridium difficile infection (CD) worldwide. Clostridium difficile has been isolated from patients with antibiotic-associated diarrhoea in Indian studies and has been implicated in all age groups. Various studies have shown prevalence ranging from 8% to 25%.
Exact prevalence is unknown. Risk factors for C.difficile infection include Elderly or immunosuppressed individual. Underlying inflammatory bowel disease. Broad spectrum antibiotic usage most commonly betalactam+ beta lactamase inhibitor combinations and third…
