Primary care physicians and hematologist often come across with patients of neutropenia, that may be either isolated or part of a complex genetic disease. Neutropenia can lead to life-threatening pyogenic infections, acute gingivostomatitis, and chronic periodontal disease, and each successive infection may leave permanent sequelae. However, the evaluation of neutropenia depends on acuity of the clinical presentation and the duration, age, and clinical status of the patient. Neutropenia (NP), is an abnormally low level of neutrophils, comprising a broad spectrum of disorders with varying clinical significance.
On one hand, there are severely neutropenic patients being either acute (e.g. drug-induced agranulocytosis or the chemotherapy-induced agranulocytosis) or chronic (e.g. the severe congenital NP). The acute and chronic condition presents the serious risk, if not appropriately…
