Solve this exciting clinical case, specific to your field of interest via Docplexus’ Clinical Case Challenge. Join your fellow doctors to discuss and answer today’s challenge. Case presentation A middle-aged man with Down syndrome visited the dental clinic with a complaint of tooth mobility. He was accompanied by his mother, who explained the medical history. The patient had recurrent pneumonia and chronic bronchitis since the age of 34 years.
Immunological assessment of the patient revealed gamma-globulinemia and beta-cell deficiency, and decreased CD45 RA + naïve CD4 + T-cells. The patient was diagnosed with gamma-globulinemia for which he had never received treatment. Radiographic examination of the oral cavity (cover image) revealed several decayed teeth and alveolar bone resorption in maxillary incisors. Marginal gingivitis and dental plaque were observed on all surfaces of the…
