Rhabdomyosarcoma originates from immature muscle cell. In pediatric patients, the tumor also originates from non-muscle progenitor cells. So, determining the origin of cells could affect the survival and treatment of patient with this disease. Cell origin determines the cell type and its location that signifies how to classify the tumor and its respective treatment. Type of cancer depends upon from where they originate.
This article emphases on Rhabdomyosarcoma cell origin, its location and trans-differentiation. During early development, the endothelial cells undergo reprogramming where it replicates more muscle cells (with characteristic) that give rise to the development of head and neck. So, this attribution explains its occurrence mainly in head and neck, even in location devoid of skeletal muscle. The cell origin determines the type of tumor. Children have this type of tumor all…
