Sedentary behavior is widely recognized as a risk factor for metabolic diseases, yet its sex-specific impact remains insufficiently understood. To address this gap, a study investigated the relationship between sedentary time and the prevalence of early-onset metabolic multimorbidity among 21,444 young adults aged 18–45 years. The analysis showed that metabolic multimorbidity was present in 25.3% of participants. The burden was markedly greater in men than in women (40.7% and 10.3%, respectively), even though women more frequently reported prolonged sedentary time.
Among men, the likelihood of metabolic multimorbidity increased progressively with longer sedentary time, while no such association was observed in women. Compared with men who spent <4 hours per day sedentary, those sitting 6–<8 hours and ≥8 hours had 22% and 26% higher odds of metabolic multimorbidity, respectively. The…
