Synopsis Obese PCOS has poor IVF outcomes associated with impaired oocyte and embryo parameters and morphology. The present study aims to evaluate the impact of low-dose liraglutide in combination with metformin compared to metformin alone on IVF PRs and cumulative PRs in infertile obese women with PCOS . This week’s “MED FACT” discusses a clinical trial from The European Journal Of Endocrinology, “Liraglutide increases IVF pregnancy rates in obese PCOS women with poor response to first-line reproductive treatments: a pilot randomized study”. Authors: Vesna Salamun et.

al. Key Takeaways: Preconception intervention with low-dose liraglutide added to metformin is superior to metformin alone in increasing PRs per ET and cumulative PRs in infertile obese women with PCOS. Objective: To evaluat e the impact of low-dose liraglutide in combination with metformin compared to metformin alone on…