Epinephrine or Adrenaline is widely used to increase blood pressure and treat cardiogenic shock resulting from acute myocardial infarction or other diseases but a recent study has shown that Epinephrine cause more mortality due to its bad effect on heart. Among all-cause cardiogenic shock patients, treatment with epinephrine was associated with a much higher risk for death.Results agree with forthcoming OptimaCC trial(included in this analysis), according to authors.
Authors: result “supports the need to reconsider the use of epinephrine in future guidelines.” Key results: 462 (18%) patients had been resuscitated after cardiac arrest. Mortality with epinephrine vs other regimen:All cohorts: 3.3 (95% CI, 2.8-3.9); Subgroup risk-adjusted for age, sex, ischemic heart disease, renal function, and ejection fraction (n=1227): 4.7 (95% CI, 3.4-6.4); 338 propensity-matched pairs: 4.2 (95% CI,…
