First Successful Human Testicular Tissue Transplant Restores Spermatogenesis A medical team at the University Hospital Brussels and the Free University of Brussels has reported a landmark case of restored sperm production following autologous testicular tissue grafting. The patient, diagnosed with sickle cell disease in 2008, underwent chemotherapy followed by stem cell transplantation. Prior to treatment, one testicle was cryopreserved in small tissue fragments.

Years later, in 2024, the preserved tissue was re-implanted at four intra-testicular and four subcutaneous scrotal sites. One-year post-procedure, active spermatogenesis was confirmed in two intra-testicular grafts—marking a significant step forward in fertility preservation strategies for prepubertal or high-risk patients. Hantavirus Updates: New Case in Spain, Exposure Quarantine in the Netherlands Spain has confirmed a new…