Background To study the prevalence of GAD antibody positivity in South Indian Type2 Diabetes individuals. Methods We studied 100 persons aged between 25 to 65 years diagnosed as Type 2 Diabetes by FBS>126mg/dl and C-peptide >0.6 ng/ml. Results 17% of Type 2 Diabetic individuals were GAD positive. 11were males and 6 were females. Distribution of GAD positivity in the age groups 25 to 34, 35 to 44, 45 to 54, >55 was 16.3%, 20.8%, 21.1% and 0 respectively.
GAD positivity with respect to the duration of diabetes 0-5 years, 5-10 years and >10 years was 18.2, 12.3 and 20% respectively. 82.4% of GAD positive type 2 diabetes individuals had BMI <25 kg/sqmt and age of onset of diabetes <50 years. Mean BMI, waist circumference and fasting C-peptide were 24.86±4.66, 87.55±10.78 and 2.49±1.41 in GAD negative Type 2 Diabetics. Mean BMI, waist circumference and fasting C-peptide were 21.65±3.46,…
