The artificial pancreas is an integrated system that monitors blood glucose levels automatically and provides insulin or a combination of insulin and a second hormone. The closed-loop system replaces reliance on testing by fingerstick or continuous glucose monitoring systems and separate, non-integrated delivery of insulin by shots or a pump. Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease affecting approximately 35 million individuals worldwide.

Current treatment requires: Multiple daily insulin injections or Continuous subcutaneous (SC) insulin infusion (CSII) delivered via an insulin infusion pump. Both treatment modes necessitate frequent blood glucose measurements to determine the daily insulin requirements for maintaining near-normal blood glucose levels. The new device consists of: A sensor is worn under clothing that transmits blood glucose readings every five…