The use of total hip arthroplasty (THA) has been continuously increasing to meet the rising demands of the elderly population. These implants are expected to support for 15-25 years in situ and they fail eventually due to slow progressive inflammatory response at the bone-implant surface. Different types of immune cells such as macrophages are triggered due to the implant wear particles. In general, immunological responses are greatly dependent on the implant material type, the size of particulate and its volume.
This article reviews different typess of immunological response initiated by biomaterials that are extensively used in THA. Total hip arthroplasties (THA) have been successful in relieving pain from the joint and restore normal joint function. This has significantly improved the quality of life, especially for many elderly patients. However, over the years the implant can fail…
