The researchers at the University of Cincinnati studied the effect of tobacco consumption in patients with kidney cancer. This Cohort research of long-term-current-smokers is published in the Journal of Clinical Investigation. The study offers the first steps to create customized therapies for patients with kidney cancer. Clear cell renal cell carcinoma(ccRCC) is the most prevalent, histologically described kidney cancer.
Multi-omics based approach has identified a distinct subtype of ccRCC in smokers as compared to the non-smoking population. Notably, this finding can be further exploited for diagnostic and prognostic biomarker development having a direct application in precision medicine. Tobacco smoking (TS) is a dose-dependent and reversible risk factor for the development of ccRCC, especially in the caucasian male. Research on TS has identified at least 70 known carcinogens and…
