I had prescribed Ceftriaxone to a 12-year-old 30 kg patient with h/o febrile illness for 5 days and serial titre rise in WIDAL and drop in TLC. The patient responded and after 5 days of treatment, continued with oral cefixime and oflox combination for another 5 days. The patient was apparently comfortable for 3 days but suddenly developed acute pain abdomen at midnight for 2 consecutive days. USG abdomen showed some deposits in GB and after 2 days radiologist opined it as multiple small calculi.
Another USG was done after 2 days and GB was absolutely clear. Gastroenterologist opined it as sludge due to Ceftriaxone. Can you comment and is it a fairly common phenomenon?
