Most anti-depressant medicines take usually 2-3 weeks for bringing good result in depressed patients and some good medicines even donot bring any good effect while Ketamine an anaesthetic agent brings good result in antidepressant in as early as within two hours. Ketamine, an anesthetic, is one of several glutamatergic drugs affecting neurotransmitters in the central nervous system. In patients with treatment-resistant major depressive disorder, ketamine produced initial reductions in depressive symptoms within two hours, with peak effects at 24 hours.
Several studies have reported "rapid, robust, and relatively sustained antidepressant response" to ketamine, injected intravenously at low, subanesthetic doses, the researchers said. Ketamine and related drugs may represent a "paradigm shift" in the treatment of major depressive disorder and bipolar depression -- especially in patients…
