Metronidazole belongs to 5 nitroimidazole groups of drug & other members in this group are tinidazole, nimorazole, dimetridazole, ornidazole having antimicrobial and antiprotozoal properties. Metronidazole first introduced in market in 1963, used in every field of medical science without much resistance, alone or with combination to other antibiotics. Uses as following: - Amoebiosis, drug of choice in diseases caused by protozoa entamoeba histolytic (in trophozoite or cystic stage) amoebiosis, dysentery or amoebic liver abscess.
Giardiasis caused by giardia lamblia 2 g od for 3 day Trichomonal vaginalis 400 mg bd for 7 days Bacterial vaginosis or gardenella vaginalis 400 mg bd for 7days Pseudomembranous colitis caused by clostridium difficillle drug of choice Helicobacter pylori for eradication with combination of azithromycin. Non-gonococcal urethritis a single dose Prophylactic to…
