Women who take selective serotonin reuptake inhibitors (SSRIs) to treat menopausal symptoms are more likely to break a bone, according to a new study. Women taking selective serotonin reuptake inhibitors (SSRIs) to treat menopausal symptoms are up to 76% more likely to break a bone, according to an observational study.
The increased risk persists for at least 5 years following initiation of SSRI treatment, suggesting that shortening treatment could reduce the risk, said senior investigator Matthew Miller, MD, of Northeastern University in Boston, and colleagues in the journal Injury Prevention. "To our knowledge, the current study is the first to examine whether SSRI use is related to fracture risks in a population of middle-aged women without known psychiatric disorders, a demographic for which, given the recent FDA approval of paroxetine for the treatment of VMS(vasomotor menopausal…
