Several molecules have been discovered and designed to target the underlying pathogenic pathway of dermal conditions. Biologics have gained further attention owing to their immunosuppressive ability. Here, we have listed a few newer molecules that have received approval from the USFDA to treat skin ailments while understanding their mechanism of action. Abbreviations: TLR – Toll-like receptor, CAM – Cyclic adenosine monophosphate, TNF – Tumor necrosis factor IL – Interleukin, LT – Leukotriene, TGF - Transforming growth factor, MITF - Microphthalmia associated transcription factor, MAPK – Mitogen-activated protein kinases   How beneficial would newer discoveries and molecules be in dermatotherapy? References Das A, Toshniwal A, Madke B. What is new in dermatotherapy?

Indian J Dermatol Venereol Leprol. 2021 Jan-Feb;87(1):135-143. doi: 10.25259/IJDVL_342_20. PMID: 33580938. Badavanis…