Electrospray deposition (ESD), an industrial spray-coating technique, can be efficiently used for the surface deposition of biological and chemical materials and can be used in transdermal drug delivery , wound healing, biosensing, and tissue engineering. The currently available ESD technique can spray materials on surfaces larger than the spray plume, with an efficiency of 40%. Now, researchers have modified ESD and tested whether it can spray particles of biologically relevant materials on micro/nano-scale on smaller surfaces with improved efficiency.
In the study, researchers used ESD to spray several materials, including bioactive small molecules, proteins, and biocompatible polymers, on flat and microneedle array targets smaller than plume size. It was found that ESD coatings achieved almost 100% efficacy. Furthermore, spectroscopy and chromatography analyses confirmed the quality…
