Nitrofurantoin retains antimicrobial activity against multidrug-resistant urinary Escherichia coli from US outpatients is an article published in J Antimicrob Chemother 2014; 69: 3259–3262 doi:10.1093/jac/dku282 Advance Access publication 25 July 2014. The conclusion is because of its consistent antimicrobial activity against MDR E. coli, nitrofurantoin remains a reliable first-line agent for the empirical treatment of acute uncomplicated cystitis. Nitrofurantoin is an antibiotic medication that is used for the treatment of uncomplicated lower urinary tract infection.
It is effective against most gram-positive and gram-negative organisms. In India, at present out of hundred culture positivity for urine culture, five Nitrofurantoin resistant is noted in our study. So, using blindly Nitrofurantoin in UTI in Indian Context is not advisable. But the present scenario of drug resistance in…
