A 2025 randomized controlled trial in Annals of Surgery compared segment 4b/5 resection and wedge resection during radical cholecystectomy for gallbladder adenocarcinoma . Among 163 patients , the 4b/5 group had longer operative time and higher blood loss , but both approaches showed similar morbidity, mortality, R0 rates, disease-free survival, and overall survival after a median 27-month follow-up. The findings suggest that the type of liver resection does not impact long-term oncologic outcomes , reinforcing a focus on surgical quality rather than extent.
To read more ; Click here Does technique matter less than precision in gallbladder cancer surgery? ##Reference## Singh, Shivendra MCh (Surgical Gastroenterology)1; Aggarwal, Abhishek MCh (Surgical Gastroenterology)1; Goel, Shaifali DNB (Surgical Gastroenterology)1; Iqbal, Syed Asif DNB (Surgical Oncology)1; Talwar, Vineet DM(Medical…
