Downs Syndrome also called trisomy 21. It is a genetic disorder patients have impairment of mental faculty and intelligence. The average intelligence is reduced to 50 percent and most of them die in the 2nd decade of life.

Downs Syndrome have a high rate of ocular manifestations. The ocular manifestations of Downs Syndrome are as follows Epicanthal fods eyes might slant upwards a little bit and are almond shaped they might have small fold of skin at inner canthus called as epicantal folds  Low visual acquity due to high rate of refractive errors 3 Astigmatism Keratoconus Nystagmus  Amblyopia Brushfield spots the outer part pf iris has light spots Presenile cataract  Glaucoma Neovascular anomalies  Prone to Alzheimer's disease Share your views.