Acromegaly is a rare but serious disease that occurs due to pituitary adenoma which causes excessive secretion of growth hormone (GH) and insulin-like growth factor 1 (IGF 1).1,2 Excess GH and IGF 1 secretion is responsible for many comorbidities like cardiovascular complications, cerebrovascular events, gonadal dysfunction, impaired glucose tolerance, diabetes, sleep apnea, impaired respiratory function, etc.1 If left untreated acromegaly results in 2-3 times higher mortality rates than the general population. Octreotide is a somatostatin analog.
Octreotide exerts pharmacologic actions similar to the natural hormone somatostatin but is a more potent inhibitor of GH, glucagon, and insulin than somatostatin. It has been approved by the USFDA as an oral prescription medicine for the long-term maintenance treatment of acromegaly in people for whom initial treatment with octreotide or…
