Hi doctors i have one question- what happen in diabetic patients if we used OHAS like sulphonamides, acarbose, bigunides if patient having creatinine more than 2. Personally i am not using. Iknow hypoglycimic events will be more. But I am asking in view of sugar control. Should we start early insulin therapy or continue OHAS.
I saw lot of preserecptions of physicians they still continue above mentioned OHAS inspite creatinine more than 2. Is it correct? What are the other effects of OHAS in CRF other than hypogycemia. Are these drugs are renal toxic? Personally i m using Glipitines and insulin in case of renal failure with diabetes.