Periodontitis is one of the leading causes of tooth loss in nearly 15% of the world population. Every time there is a dysbiosis in the dental plaque constituents, the inflammation of gingival tissue occurs, which may further progress into the formation of periodontal pockets and bone loss, leading to tooth mobility of varying severity. Periodontal therapies and regenerative procedures can combat inflammatory responses and restore lost structures.
The most common techniques known so far are guided tissue and bone regeneration by using bone grafts, incorporation of growth factors by PRP or PRF, use of enamel matrix derivatives, collagen, or titanium mesh. The recent advances speak of tissue engineering and stem cells derived from bone marrow, periodontal ligament, or dental pulp; however, the success rate continues to be unpredictable due to the technique sensitivity of these procedures…
