Glioblastoma, being a serious recurrent condition, is worked upon tremendously and recent research has given a diverse way for its management with poliovirus. Although poliovirus is hazardous for humans, its modified form infects the tumor cells without harming the nerves. The strong immune system response catered by poliovirus has led to this research.
Glioblastoma and Oncolytic Virotherapy Glioblastoma and polio, both deteriorating the health of patients, can now be brought on the same platform as poliovirus is proved to fight against brain tumour. Glioblastoma multiforme (GBM), the most common and malignant form of primary brain tumor, is characterized by rapid invasive growth, and genetic and histological heterogeneity. The major problems associated with it, resistance to most chemotherapeutic drugs and local recurrence, make its management challenging with only 12-15 months of…
