Pre-emptive analgesia is an antinociceptive treatment that prevents establishment of altered processing of afferent input, which amplifies postoperative pain. Concept of preemptive analgesia was formulated by Crile DEFINITION : Treatment that: Starts before surgery Prevents the establishment of central sensitization by incisional injury ( covers period of surgery) Prevents establishment of central sensitization caused by incisional and inflammatory injury (covers the period of surgery and the initial postoperative period). Strategies: Local skin infiltration-pre and post operative PCM and NSAIDS: reduces inflammation, pain , fever: Diclofenac - used in orally, per-rectally,intramuscularly and continuous infusion.Single dose: 1.0 - 2.0 mg/kg; maximum dose; 3mg /kg /day.
Interval: 6- 8 hours. Paracetamol - can be administered in orally, infusion and per-rectally. Single dose: 10 - 15…
