Regional Anaesthesia in Complex Patients: Are New Evidence-Based Guidelines the Missing Link? Regional anaesthesia continues to reshape perioperative care through improved analgesia, faster recovery, and opioid-sparing benefits, yet its use in anticoagulated or comorbid patients remains clinically challenging. These multidisciplinary guidelines developed under SIAARTI using the GRADE framework provide structured recommendations addressing neuraxial blocks in anticoagulated patients, dual-guidance techniques for peripheral nerve blocks, sterile field preparation, and post-procedural monitoring.

Evidence from meta-analyses and large observational studies supports many recommendations, although heterogeneity in available data persists. The guidance offers clinicians a practical safety framework while highlighting key evidence gaps requiring further research. Read the full guideline to…