Evidence suggests impaired spermatozoa immunogenicity can complicate pregnancy and cause recurrent spontaneous abortion (RSA). Since spermatozoa are exposed to microbiota both in the male and female reproductive tracts, there are high chances of harmful microbiota altering the antigenicity of the spermatozoa. Given the proven benefits of probiotics in treating several female reproductive disorders such as vaginosis, candidiasis, and preeclampsia, it may be of interest to determine the efficacy of probiotics in preventing recurrent spontaneous abortion (RSA).
Here's a Journal Watch that discusses the study “ The effect of probiotics on the immunogenicity of spermatozoa in couples suffering from recurrent spontaneous abortion ” from BMC Immunology, 2022 . What was the need for the study? To date, the effects of probiotics on spermatozoa immunogenicity have not been investigated, even…
