General anaesthetics are administered to around ten millions of patients every year on earth, profol is becoming intravenous anaethetic, drug of choice in ambulatory surgery. First isopropyl phenol introduced in 1980 by imperial college of london, and for use in 1986,research in past become useful to patient safety, few important research in field of anaesthesiology are: 1846 ether introduced in Boston by dentist 1885 cocaine as local anaesthetic agent.

1896 injection of morphine 1905 blood pressure cuff 1913 endotracheal tube 1930 sodium thiopental pentothal 1940 muscle relaxant curare 1950 intensive care units 1983 pulse oxymetry 1986 propofol Propofol is 2,6 di iso propyl phenol obtained by heating phenol with propene, and is supplied in market in 1% concentration as 10mgm/ml in 20 to 100 ml vial for anaesthetic use with other following things: Soyabean oil 10% 100 mgm/ml Glycerin…