Early recognition of clinical red flags in the OPD and emergency setting can be lifesaving. While many patients present with common, benign complaints, a small proportion harbor serious underlying pathology. Missing these warning signs often leads to delayed diagnosis, poor outcomes, and medico-legal consequences. A high index of suspicion and systematic assessment are therefore essential. DO NOT ignore abnormal vital signs.

Unexplained tachycardia, hypotension, tachypnea, hypoxia, or altered temperature should always prompt urgent evaluation, even if the patient appears clinically stable. In both OPD and emergency settings, subtle vital sign abnormalities may be the earliest indicators of sepsis, internal bleeding, pulmonary embolism, or cardiac events. Normal appearance should never override objective parameters. Pain with atypical features is a major red flag. Severe pain…