Gastrointestinal tract in human body start from oral orifice & ends at anal orifice. Colon is part of large intestine start from cecum to rectum. Colon has mainly absorptive function & storage / propulsion of fecal matter. Normal colon emptying can be disrupted due to constipation/obstruction.

Due  delayed emptying  of colon it  become  loaded  with fecal matter & will  have  negative feedback  on small intestinal  motility/chyme movement & positive  feedback  on PANCREASE to continue secretion of insulin & later  pancreatic tissue get fatigued   insulin  level  decreased & results in hyperglycemia /NIDDM in adults. Colon emptying can be promoted by ingestion of green leafy vegetables Fruits  Water & salt maintenance in body Physical activity daily basis / exercise Restricted intake of alcohol /smoking & others. Does this loaded colon has high impact on NIDDM? Or Regular easy colon…