. Early diagnosis of colorectal cancer (CRC) is critical to providing timely treatment to patients, and colonoscopy is the gold standard for its diagnosis. However, colonoscopy is an invasive and expensive diagnostic technique; therefore, there is a need to identify more reliable and noninvasive diagnostic biomarkers. Recently, researchers from Nagoya City University, Japan, have identified novel urinary microRNA (miRNA) biomarkers that can aid in the early detection of colorectal cancer.
CRC is commonly diagnosed with invasive and expensive colonoscopy examinations. In addition, a fecal immunochemical test (FIT) was also developed to find hemoglobin and CRC DNA markers in the fecal samples. However, FIT has several drawbacks, including bacteria in fecal samples and the production of false-positive results, which have to be confirmed by colonoscopy. In addition, several studies indicate…
