Current antiretroviral therapy (ART) suppresses HIV replication, decreases viral load, prevents HIV transmission and prolongs survival of the patient. However, ART does not completely cure HIV infection as the virus remains in the latent state in immune cells and hence does not get targeted by ART. A recent study has identified where the virus hides during its latent state and this can help designing new therapeutic approaches. Despite a lot of research, completely eliminating HIV infection still remains a challenge. According to the studies done till now.
We know that only 5% of the virus is genetically intact and remaining virus makes a lot of errors during replication. But it is this 5% population which resides in T cells and avoids detection by the immune system. This is the major reason why the virus does not get completely eliminated from the body. The infected immune cells go…
