Patient History: A 6-year-old boy presents to the emergency department with his parents after accidentally ingesting one nadolol tablet. One hour following the ingestion, the child became dizzy and vomited. Because the child appeared to be very sleepy, the parents brought him in for evaluation. Physical Examination: Temperature 98.6°F HR: 100 bpm RR: 22 breaths per minute BP: 100/60 mm Hg General: Sleepy, but easily aroused. HEENT: Normocephalic, pupils equal and reactive to light. Pulmonary: Clear to auscultation CV: Regular rate and rhythm.

Neurologic: Unremarkable. What is the mechanism by which β-blockers cause toxicity? What will be your next step in this condition? *This patient case is from Docplexus Editorial Team for educative purposes only. Source: Pharmacology and Toxicology Case Studies.